Effect of Raphanus Sativus (Radish) Leaf Extract and High Doses of Atorvastatin on Lipid Profile

Effect of Raphanus Sativus (Radish) on Lipid Profile

  • Obaid Anwar Associate Professor, Department of Pharmacology, Abwa Medical College, Faisalabad, Pakistan
  • Hafiz Muhammed Imran Aziz Assistant Professor, Department of Pharmacology, Bakhtawar Amin Medical College, Multan Pakistan
  • Asad Mahmood Khan Professor, Department of Pharmacology, Sahiwal Medical College, Sahiwal Pakistan
  • Rehana Ramzan Ph.D. Scholar, Department of Biochemistry, Government College University, Faisalabad Pakistan
  • Saleha Shafi Department of Pharmacy, The University of Faisalabad, Faisalabad Pakistan
  • Zobia Mushtaq Professor, Department of Pharmacology, Gujranwala Medical College, Gujranwala Pakistan
Keywords: LDL, HDL, Atorvastatin, Raphanus sativus


Background: Hyperlipidemia is a key component in a devastating chain reaction that ultimately results in mortality among the elderly. Atorvastatin is the most commonly advised statin to patients suffering from hyperlipidemia. Raphanus Sativus (R Sativus) commonly used in salads contains many antioxidants. Objective: To determine the effect of Raphanus Sativus (Radish) leaf extract and high doses of Atorvastatin on Lipid Profile. Study Design: Randomized control trail (RCT). Settings: Pharmacology department, Faisalabad Medical University, Faisalabad Pakistan. Duration: 3 Months from July 2020 to September 2020. Methods: Ethanolic extract of R Sativus was screened for beneficial effects on lipid profile by atorvastatin. Results: Findings were compared with both the normal and experimental control by assessing the different components of the lipid profile, such as the LDL, HDL, triglycerides, and serum cholesterol. There was a substantial decrease in weight observed in all groups compared to the negative control group A. Conclusion: Ethanolic extract of leaves of radish used in three increasing doses has a significant effect on lipid profile in albino rabbits when used along with atorvastatin.

How to Cite
Anwar, O., Aziz, H. M. I., Khan, A. M., Ramzan, R., Shafi, S., & Mushtaq, Z. (2024). Effect of Raphanus Sativus (Radish) Leaf Extract and High Doses of Atorvastatin on Lipid Profile: Effect of Raphanus Sativus (Radish) on Lipid Profile. Annals of Punjab Medical College, 18(2), 141-144. https://doi.org/10.29054/apmc/2024.1543