Effect of Raphanus Sativus (Radish) Leaf Extract and High Doses of Atorvastatin on Lipid Profile

Effect of Raphanus Sativus (Radish) on Lipid Profile

Abstract

Background: Hyperlipidemia is a key component in a devastating chain reaction that ultimately results in mortality among the elderly. Atorvastatin is the most commonly advised statin to patients suffering from hyperlipidemia. Raphanus Sativus (R Sativus) commonly used in salads contains many antioxidants. Objective: To determine the effect of Raphanus Sativus (Radish) leaf extract and high doses of Atorvastatin on Lipid Profile. Study Design: Randomized control trail (RCT). Settings: Pharmacology department, Faisalabad Medical University, Faisalabad Pakistan. Duration: 3 Months from July 2020 to September 2020. Methods: Ethanolic extract of R Sativus was screened for beneficial effects on lipid profile by atorvastatin. Results: Findings were compared with both the normal and experimental control by assessing the different components of the lipid profile, such as the LDL, HDL, triglycerides, and serum cholesterol. There was a substantial decrease in weight observed in all groups compared to the negative control group A. Conclusion: Ethanolic extract of leaves of radish used in three increasing doses has a significant effect on lipid profile in albino rabbits when used along with atorvastatin.