Correlation of Menstrual Irregularities with Thyroid Disorders in Infertile Women

Abstract

Background: In current era menstrual irregularities are very common problem mainly in adulthood age. It creates a lot of stress not only on the social behavior of females but can also leads to infertility especially if it is related to hormonal imbalance. Among them, thyroid dysfunction can result in reproductive cycle problems like menorrhagia which is commonly seen in hypothyroid females. Objective: The aim of this study was to highlight menstrual disorders & investigate thyroid hormone levels in both fertile & infertile women. As it will help us to evaluate the correlation between menstrual irregularities & hypo- and hyperthyroidism. Study Design: A case control study, patients were analyzed by the help of questionnaire which include history, clinical examination & laboratory investigations. Settings: This clinical study was done in Gynecology Department of Madinah Teaching Hospital, Faisalabad Pakistan. Duration: 6 months from February 2018 to July 2018. Methods: Almost 132 females belonging to 20-35 years of age were selected, among them 86 females were infertile & 46 were fertile. Results: Results were evaluated by SPSS version 20. Most of the infertile women were euthyroid and hyperthyroidism was more common among them. The prevalence of hyperthyroidism and hypothyroidism was about 26.7% and 9.3% respectively. Almost all infertile females with thyroid disorders showed menstrual irregularities. Thyroid hormonal status was also assessed with different types of menstrual disarrays and it was non-significant. Conclusion: Thyroid profile should be recommended to those infertile women who are having menstrual irregularities so that other needless investigations can be avoided. Evaluation of thyroid status in an infertile couple is important and easy. Its treatment is simple and has reversible or preventable effects on subfertility.