Effects of Red Meat Consumption on Histology of Coronary Arteries in Adult Albino Mice

Abstract

Objective: To determine the effects of the red meat (Buffalo) on coronary arteries of adult albino male Mice. Study Design: Experimental study. Settings: Anatomy Department of Liaquat University of Medical and Health Sciences, Jamshoro in collaboration with animal house of Sindh Agriculture University Tando Jam. Duration: 6 months from January 2017 to July 2017. Methodology: Total 45 adult Albino male mice (laboratory male mice) of average 180–220 grams bodyweight was selected. Animals were housed (about 4-6 per cage) in a temperature-controlled room (22± 2°C) and at a humidity of 55%±5%, with a 12-hr light/dark cycle. Animals were divided into three groups as: group A (control), group B white meat (poultry) and group C (red meat). At the end of the experiment animals were sacrificed and hearts were taken from every animal as soon as possible and specimens were assessed for histopathology. Results: Mean cholesterol level was significantly higher among red meat consuming group as compared to control group (P- 0.001). Mean body weight was markedly higher among red meat consuming group in contrast to control group; p-values were quite significant. Total 6.66% mice suffered in red meat consuming group and out of them 3.34% died. Conclusion: It was concluded that red meat consumption is associated to a higher risk of cholesterol elevation and mortality, without any histological alteration.