Incidence of SIRS in Acute Biliary Pancreatitis

Abstract

Objective: To see the incidence of systemic inflammatory response syndrome (SIRS) in acute biliary pancreatitis. Setting: Department of surgery, Armed Forces Hospital Dhahran, Saudi Arabia.  Period: From January 2001 to January 2009. Patients and methods: Clinical and biochemical data of 102 patients of acute biliary pancreatitis was analyzed retrospectively. Acute biliary pancreatitis was more common in females (74.5% vs. 25.5%) with a female to male ratio of 2.9:1. Majority of patients (70.6%) were in the age range of 21-50 years. All patients had ultrasound abdomen, hemoglobin, TLC, BUN, Creatinine, blood gases, liver function tests, serum amylase and lipaseComputed tomography of abdomen (CT) was done in 16 (15.69%) patients and ERCP was done in 30 (29.4%) patients. Results: Only 2 patients had fever and leukocytosis consistent with SIRS whereas 8 (7.8%) had fever above 38⁰C only and another group of 22 (21.6%) patients had TLC >12000 cu mm. Clinical and biochemical abnormalities normalized in almost all patients within 72 hours. Conclusion: The group of patients who do not show SIRS and their clinical and biochemical abnormalities settle quickly should be named differently for statistical correction and management. Key words: acute biliary pancreatitis, systemic inflammatory response syndrome