Efficacy of Arthemether-Lamefuntrine In Malaria

Saif  Ullah; Mirza Akmal Sharif; Umair  Ahmad

doi:10.29054/apmc/2012.482

Saif Ullah Assistant Professor Medicine Sargodha Medical College, Sargodha
Mirza Akmal Sharif Associate Professor Medicine Punjab Medical College, Faisalabad
Umair Ahmad Senior Registrar Medicine Allied Hospital, Faisalabad

DOI: https://doi.org/10.29054/apmc/2012.482

Keywords: Malaria, Arthemether-Lamefuntrine (AL), Malarial Parasite

Abstract

Objective: To determine the efficacy of Arthemether-Lamefuntrine (AL) in patients with malaria. Study Design: Quasi-experimental study. Place and Duration of study: Study was conducted in Medical Unit DHQ Hospital Sargodha and Medical Unit V, DHQ Hospital Faisalabad from 1^st January 2011 to 30 June 2011. Subjects and Methods: 129 adult patients both male and female diagnosed to have malaria both on clinical and laboratory examination were included in the study. Patients were given AL (20/120) 2 tablets 12 hourly for three days. An adequate clinical and parasitological response (ACPR) was defined as absence of fever and parasitaemia (negative slide for Malarial parasite) by day 45 after end of treatment. Results: Out of 129 patients adequate response (ACPR) was seen in 122 patients with efficacy of 94.6%. Conclusion: AL is an important and effective treatment option for treatment of patients with malaria.