Clinicopathological Pattern of Breast Cancer Presentation in Allied Hospital Faisalabad

Abstract

Objective: To determine the pattern of presentation of breast cancer in Allied Hospital Faisalabad regarding age, stage, histological type, tumor grade and receptor status. Study design: An observational study. Settings: Department of Surgery Allied Hospital Faisalabad-Pakistan. Duration: January 2014 and January 2015. Methodology: 500 diagnosed breast cancer patients, who were either treated surgically or referred to Oncology department for neo adjuvant or adjuvant therapy, were included in the study after obtaining informed consent. Patients were interviewed using a questionnaire. Staging was done using triple assessment and relevant investigations and then followed for histopathology reports for histological type, grade, margin clearance and receptor status for ER, PR, and HER 2 Neu receptors. The collected data was analyzed using SPSS version 17. 0. Results: In this study, 500 patients were included with age ranging from 23 years to 80 years. 40 to 50 years is the most prevalent age group for carcinoma breast (57%). 64% females presented with advanced breast cancer (stage III and IV). Invasive ductal carcinoma is the commonest pathological type (93%). Majority (55%) of patients had grade II tumors on histopathology. Conclusion: According to this study majority of the patients presented between 40-50 years. Invasive ductal cell carcinoma is the most common type. Majority of the patients presents in advance stage.