Comparison of Polyglactin (Vicryl) Versus Polydioxanone (PDS) Suture in Sub-Coronal Hypospadias Repair in Terms of Urethrocutaneous Fistula Development
Keywords:
Hypospadias, Polydioxanone (PDS) suture, Polyglactin suture, Urethrocutaneous fistulaAbstract
Introduction: Delayable absorbable sutures like polydioxanone may reduce urethrocutaneous fistula, but some surgeons warn they could cause urethral stricture due to long-term tissue irritation. Various surgical techniques have evolved to manage this anomaly, but little research exists on the Pakistan Health sector's comparison of polyglactin (VICRYL) versus polydioxanone (PDS) sutures in pediatric hypospadias repair. The purpose of this study is to compare the Polyglactin (VICRYL) versus Polydioxanone (PDS) suture in hypospadias repair regarding the frequency of urethrocutaneous fistula development.
Materials & Methods: A randomized controlled trial was conducted at Allied Hospital, Faisalabad from 8th July 2023 to 7th July 2024 involving 150 male patients aged 1 to 5 years with subcoronal hypospadias. Patients with previous hypospadias repair, pre-surgical testosterone stimulation, or other urogenital anomalies were excluded. Patients were divided into two groups: VICRYL (Polyglactin5/0 sutures) and PDS (Polydioxanone5/0 sutures) for urethroplasty. Postoperative assessment focused on the development of urethrocutaneous fistula, confirmed through clinical examination during follow-up.
Results: In this study, urethrocutaneous fistula in group V (Polyglactin (VICRYL)) was found in 24.0% of patients, and in group P (Polydioxanone (PDS) suture) was 10.67% (p-value = 0.031).
Conclusion: This study concluded that the frequency of urethrocutaneous fistula development is less with Polydioxanone suture in hypospadias repair as compared to Polyglactin suture.
