Nano Fat Graft Harvested from Abdomen in Comparison with Thigh in the Treatment of Hyperpigmentation of Face

Nano Fat Graft: A Novel Technique for Hyperpigmentation

Abstract

Objective: To evaluate the outcomes of nano fat graft harvested from abdomen in comparison with thigh in the treatment of hyperpigmentation of face. Study Design: Randomized control trial. Settings: Plastic and Reconstructive Surgery department, Lahore General Hospital, Lahore Pakistan. Duration: 2 years January 2021-December 2023. Methods: The tissue thickness was also assessed through ultrasonographical imaging in all patients. Cases enrolled were divided into two groups wherein Group I was those cases where Nano fat graft was generated from the medial thigh fat while Group II were those cases where the abdomen region fat was used for the formation of the fat graft. A 10-cc syringe (14G needle) in multiple layers was used for injecting fat graft under local anesthesia.  Over corrections were performed up to 20-30% for due to absorption chance. Postoperative ultrasonography was performed and tissue thickness was observed after 3 months for comparing the fat survival and thickness rate. Results: The fat thickness in the application of medial thigh fat graft group I was observed slightly higher than the abdomen-based fat graft generated, although the variance was insignificant. It was observed that the rate of complications like bruising and pain was higher in the group I while seroma was lowed in group I than Group II. Conclusion: The Nano fat graft generated from the fat tissues of the medial thigh has higher efficacy and survival rate with lack of lethal complications than the nano graft generated form the abdomen fats.