Clinical Manifestations of Adenomyosis Confirmed via Histopathological Examination of Hysterectomy Specimens

Faiza Saeed; Shumaila Najeeb; Arfa Naeem; Santosh Kumar Sidhwani; Syed Muhammad Ishaque; Muhammad Wasif Saleem

doi:10.29054/apmc/2022.1429

Faiza Saeed Senior Registrar, Department of Gynaecology And Obstetrics, Shahida Islam Medical Complex, Lodhran Pakistan
Shumaila Najeeb Associate Professor, Department of Histopathology, Mohiuddin Islamic medical College, AJK Pakistan
Arfa Naeem Senior Demonstrator, Department of Pathology Central Park Medical College & Teaching Hospital Lahore Pakistan
Santosh Kumar Sidhwani Associate Professor, Department of Pathology, Mekran Medical College, Turbat Pakistan
Syed Muhammad Ishaque Associate Professor, Department of Pathology, Bolan Medical College, Sandman Provincial Civil Hospital, Quetta Pakistan
Muhammad Wasif Saleem Assistant Professor, Department of Pathology, Mekran Medical College, Turbat Pakistan

DOI: https://doi.org/10.29054/apmc/2022.1429

Keywords: Adenomyosis, Chronic pelvic pain, Dysmenorrhea, Histopathology, Hysterectomy, Menorrhagia, Uterine conditions

Abstract

Background: Adenomyosis is a benign uterine condition characterized by the presence of endometrial tissue within the myometrium, leading to symptoms such as menorrhagia, dysmenorrhea, and chronic pelvic pain. Accurate diagnosis often requires histopathological examination of hysterectomy specimens due to the limitations of imaging techniques. Objective: To evaluate the clinical manifestations of adenomyosis and their correlation with histopathological findings in hysterectomy specimens. Study Design: Cross-sectional study. Settings: Department of Department of Pathology, Mekran Medical College, Turbat Pakistan. Duration: From 17 May 2021 to 17 December 2021. Methods: Patients were reviewed for demographic data, presenting symptoms, and histopathological findings. A total of 130 hysterectomy specimens were examined, with adenomyosis confirmed in 102 cases (78.5%). Symptoms such as menorrhagia, dysmenorrhea, and chronic pelvic pain were analyzed in relation to the histopathological severity of adenomyosis. Statistical analysis was performed to assess the correlation between clinical symptoms and histopathological findings. Results: Menorrhagia (89.2%) and dysmenorrhea (83.3%) were the most common symptoms among patients with confirmed adenomyosis. Histopathological examination revealed diffuse adenomyosis in 60.8% of cases and focal adenomyosis in 39.2%. The severity of adenomyosis was significantly correlated with the intensity of symptoms (p < 0.05). Conclusion: Our study highlights the critical role of histopathological examination in diagnosing adenomyosis and its correlation with clinical manifestations. Accurate diagnosis is essential for effective management and improving patient outcomes.