Rosai Dorfman’s Disease

Abstract

This fascinating disorder is also known as sinus histiocytosis with massive lymphadenopathy (SHML). The most common presentation is massive painless bilateral lymphadenopathy with fever. The disease has a predilection for blacks. In few cases extranodal areas may be involved. Importance of this disease is its capacity to simulate a malignant process, both clinically and pathologically.  It has a benign clinical course