Frequency of Cervical Intraepithelial Neoplasia in Women Attending Allied Hospital, Faisalabad

Abstract

Objective: To determine the frequency of cervical intraepithelial neoplasia (CIN) with papanicolaou (PAP) smear and identifying the disease in pre- malignant phase, thus preventing the development of invasive cancer. Study Design: Observational type of study. Place and duration of study: Outpatient department of Obstetrics & Gynaecology of Allied Hospital, Faisalabad from Jan. 2003 to Dec. 2003. Patients & Methods:  All the patients  attending the Gynae outpatient department at Allied Hospital, Faisalabad with Gynaecological symptoms were subjected to a detailed history, examination and then underwent papanicolaou smear cytology with wooden Ayers Spatula. Patients having vulvovaginitis, menstruation and obvious cervical growth were excluded. The smear was sent to College, Faisalabad. Results: A total of 500 patients underwent cervical cytology. 47 patients (9.4%) showed positive smears, while 453 patients (90.6%) were negative for cytology. Out of 47 patients 22 (46%) were found to have CIN - I, 13 (27%) CIN - II, 8 (17%) CIN - III and 4 patients (8.5%) showed invasive cancer. Majority of patients (51%) with positive smear were between ages (35-44 years), grand multiparous, presented with abnormal vaginal discharge and belonging to lower social economic status. Conclusion: Study shows that our population have significant number of premalignant cervical disease. So screening with pap. smear should have wide application all over the Pakistan to reduce the incidence of cervical cancer. Key Words: Papanicolaou smear, cervical intraepithelial neoplasia prevention