Etiological Spectrum of Liver Cirrhosis Patients Presenting to a Tertiary care Hospital in Pakistan

Muhammad Irfan; Muhammad Arif Nadeem; Sabeen Farhan; Ishtiaq Bokhari; Sadaf Yousaf; Aftab Mohsin

doi:10.29054/apmc/2011.531

Muhammad Irfan Senior Registrar in Medicine Services Hospital, Lahore
Muhammad Arif Nadeem Assistant Professor of Medicine SIMS / Services Hospital, Lahore
Sabeen Farhan Senior Registrar in Medicine Services Hospital, Lahore
Ishtiaq Bokhari Postgraduate Resident in Gastroenterology Services Hospital, Lahore
Sadaf Yousaf Registrar in Medicine Services Hospital, Lahore
Aftab Mohsin Professor of Medicine SIMS / Services Hospital, Lahore

DOI: https://doi.org/10.29054/apmc/2011.531

Keywords: Liver cirrhosis, Hepatitis C

Abstract

Objectives: To determine the etiological spectrum in patients of Liver cirrhosis presenting to a tertiary care hospital of Pakistan. Study: A descriptive case series conducted from December, 2006 to December, 2007 at Services Hospital Lahore. Patients and Methods: One hundred patients of liver cirrhosis presenting in emergency or outpatient department of Services Hospital Lahore, were enrolled. Diagnosis of cirrhosis was made by combination of clinical and ultrasonographic findings. ELISA testing for Hepatitis B surface antigen and Hepatitis C virus antibodies was performed. Results: Amongst the 100 patients 59% were male and 41% were females, majority of these had urban (82%) background. The etiology of cirrhosis was mainly viral (83%), out of which 81% had hepatitis C, 1% hepatitis B and 1% both hepatitis B and hepatitis C. The mean age (years) was 55.79 ± 13.545 (SD) and mean weight (kilograms) was 62.49 ± 8.02 ((SD). Conclusion: We conclude that etiology of Liver Cirrhosis is mainly Hepatitis C in our areas and males are more vulnerable to acquire.