Role and Effectiveness of Intraperitoneal Bupivacaine in Post-Operative Pain Management after Laparoscopic Cholecystectomy

  • Lal Shehbaz Resident Emergency Medicine Department of Emergency Medicine, Ziauddin University Hospital, Karachi
  • Bashir Ahmed Assistant Professor, Anesthesiology and Surgical ICU, Dow University of Health Sciences, Civil Hospital, Karachi
  • Kamlaish . Consultant Anesthetist, Dow University of Health Sciences, Civil Hospital, Karachi
  • Saqib Basar House officer, Dow University of Health Sciences, Civil Hospital, Karachi
  • Ahmed Ali Research Fellow Karachi
Keywords: intra peritoneal bupivacaine, laparoscopic cholecystectomy, post-operative pain management


To study the effectiveness of intraperitoneal bupivacaine in the pain management of patients who had laparoscopic cholecystectomy, and comparison with a control group. Objectives: The purpose of the study is to find out the efficacy of intraperitoneal bupivacaine injection, for post-operative pain management in patients following laparoscopic cholecystectomy. Material & Methods: The method of study is a randomized control trial, Two groups of people were selected at random from a pool of 100 patients, each group had 50 patients each. One group did not receive intraperitoneal bupivacaine, while the other group was injected 20ml of bupivacaine (.25%) intraperitoneally, in the sub diaphragmatic space on the right side along with in the bed of the gall bladder.  Results: The post-operative mean abdominal pain score using the VAS scale in both groups was calculated using at different intervals and recorded as 1.34 +/-0.43 cm in the control group and 2.54 +/- 0.26 cm in the bupivacaine group at zero hours, , 2.11 +/- 0.32 cm in control group and 2.98 +/- 0.54 cm in bupivacaine group at two hours, 2.98 +/- 1.05 cm in control group and 3.24 +/- 0.84 cm in bupivacaine group at four hours while 3.13 +/- 1.21 cm in control group and 4.59 +/- 1.32 cm in bupivacaine group at six hours were recorded. The efficacy is recorded as 36.67% in control group and 6.67% in bupivacaine group while 63.33% in control group and 93.33% in bupivacaine group. Conclusion: For post-operative pain relief in laparoscopic cholecystectomy patients, intra peritoneal bupivacaine injection is an effective method.